Table 1.
Clinical characteristics of 33 patients at time of enrollment
| Age, y | 51.8 (SD 12.4) |
| Male | 20 (60.6) |
| Offered ICD prior to study | 25 (75.8) |
| ESC 5-year risk of sudden cardiac death | |
| Low risk (< 4%) | 20 (60.6) |
| Moderate risk (4%–6%) | 9 (27.3) |
| High risk (> 6%) | 4 (12.1) |
| AHA/ACC classification | |
| Class I | 0 (0.0) |
| Class IIA | 18 (54.5) |
| Class IIB | 9 (27.3) |
| Class III | 6 (18.2) |
| Risk factors | |
| Family history of sudden cardiac death | 6 (18.2) |
| Maximum wall thickness, mm | 21.7 (SD 4.9) |
| Unexplained syncope | 8 (24.2) |
| Prior nonsustained ventricular tachycardia | 11 (33.3) |
| Abnormal blood pressure response to exercise | 4 (12.1) |
| Left atrial diameter, mm | 41.6 (SD 7.7) |
| Maximum left ventricular outflow gradient | 30.1 (SD 34.9) |
| Late gadolinium enhancement | 25 (75.8) |
| Left apical aneurysm | 4 (12.1) |
| LVEF | 64% (SD 7.3) |
| Alcohol septal ablation | 1 (3.0) |
| Septal myectomy | 2 (6.1) |
| Genetic variants | |
| Pathogenic | 5 (15.2) |
| Likely pathogenic | 7 (21.2) |
| Variant of unknown significance | 5 (15.2) |
| Medications | |
| Beta-blocker | 17 (51.5) |
| Calcium-channel blocker | 10 (30.3) |
| Disopyramide | 2 (6.1) |
Values are n (%) or mean (SD).
ESC, European Society of Cardiology; AHA/ACC, American Heart Association/American College of Cardiology; ICD, implantable cardioverter defibrillator; LVEF, left ventricular ejection fraction; SD, standard deviation.