FIGURE 4.

Tumor fluid flows and fluxes. A graph of changes in cerebral blood flow (CBF), blood-to-brain forward volumetric transfer constant (Ktrans), tumor interstitial fluid pressure (TIFP) and peri-tumoral interstitial fluid flow (Flux) at times after Avastin (10 mg/kg; iv) treatment. The values are plotted as mean ± standard error of the mean % differences between the pre- and post-treatment values. Asterisks represent significant difference, p < 0.05