TABLE 1.

Fixed-Effect Percentage Change from Previous Cycle

	Change (% from previous cycle)
	G1		G2
Dependent variable	Mean	95% CI	Mean	95% CI	P (G1 vs. G2)
Activity concentration (MBq/mL)	−6.1	−11 to −0.89	−14	−20 to −8.4	0.04
Absorbed-dose rate (mGy/h)	−6.2	−11 to −0.93	−14	−20 to −8.3	0.04
Effective half-time (h)	−0.69	−2.1 to 0.77	−1.2	−3.4 to 1.1	0.7
Volume (cm3)	−1.1	−5.0 to 3.0	−6.4	−11 to −1.4	0.1
AD (Gy)	−5.7	−11 to −0.12	−14	−20 to −7.9	0.04

Data are calculated from rates of change from the LMM, such that for G1, change = $\exp \left(k_1\right)-1$, and for G2, change = $\exp \left(k_1+k_2\right)-1$, with $k_1$ and $k_2$ as in Eq.1.