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(A) Significant decrease in tspo, csf-1r, and tmem119 gene expression with treatment in both wild-type and stroke animals. (B) Efficient downregulation of gene transcription for several proinflammatory, antiinflammatory, and phagocytosis-relevant genes on CSF-1R inhibition. mRNA = messenger RNA. ###P < 0.005 vs. treatment. &P < 0.05 vs. wild-type mice. &&&P < 0.005 vs. wild-type mice.
