FIGURE 4.
(A) MRI demonstrates contrast enhancement in recurrent right frontal glioma, with viable tissue predominately seen posteriorly. (B) Summed 20- to 60-min 2-[11C-11]thymidine PET image demonstrates relatively high background uptake of tracer throughout brain, with mildly increased tracer uptake in enhancing portion of recurrent glioma. (C) 2-[11C-11]thymidine Ki parametric image from mixture analysis demonstrates increased contrast of tumor compared with normal brain, underscoring benefits of kinetic analysis. (Modified with permission of (57).)