TABLE 3.
Association between medication parameters and HbA1c level (≤7.0%) of study cohort from “EnPHC-Eva: Facility” Malaysia, 2018-2019.
| Unadjusted | Adjusted | |||
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | p-value | R 2 | |
| Patient-level | ||||
| Medication count | 0.92 (0.87, 0.96) | 0.88 (0.82, 0.94) | <0.001 | 0.0862 |
| MRCI score | 0.91 (0.89, 0.92) | 0.89 (0.87, 0.92) | <0.001 | 0.1126 |
| Adherence (PDC) | 1.91 (1.10, 3.31) | 2.66 (1.66, 5.19) | 0.004 | 0.0840 |
| Diabetes-specific | ||||
| Medication count | 0.54 (0.48, 0.61) | 0.59 (0.52, 0.66) | <0.001 | 0.1003 |
| MRCI score | 0.68 (0.66, 0.71) | 0.70 (0.67, 0.74) | <0.001 | 0.1900 |
| Adherence (PDC) | 1.11 (0.65, 1.89) | 1.76 (0.86, 3.60) | 0.123 | 0.0819 |
Note: Model was run separately for (i) medication count, (ii) MRCI, score, and (iii) adherence. Estimation using univariate (unadjusted) and multiple logistic regression adjusted for age (years), gender (male/female), ethnicity (Malay/Chinese/Indian/others), hypertension (no/yes), hyperlipidaemia (no/yes), body mass index (kg/m2), location of primary care clinic (rural/urban), duration of diabetes (years). p-value significant at <0.05. The variance inflation factors (VIFs) for all variables were less than two in all models. Abbreviations: OR, odds ratio; CI, confidence interval; MRCI, medication regimen complexity index; PDC, proportion days covered.