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. 2022 Apr 4;11:20. doi: 10.1186/s40164-022-00275-0

Fig. 2.

Fig. 2

Voluntary running improved the effect of combination therapy in HCC mouse model. A Average running distance per mouse per week in the combination therapy plus physical activity group. B Tumor growth and C survival (time to 20 mm in maximum diameter) of subcutaneously implanted HCC mice. D Tumor viability assessed in Hematoxylin and eosin slides from the subcutaneous HCC mouse model. Representative images captured at 40 ×. * P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. HCC hepatocellular carcinoma