Table 2.
Adverse Outcome Pathways and Their Properties in Resource Description Framework
| Predicate | Object | Object example |
|---|---|---|
| Adverse outcome pathway | ||
| a | aopo:AdverseOutcomePathway | |
| dc:identifier | Adverse Outcome Pathway (IRI) | aop:38 |
| rdfs:label | Label (literal) | “AOP 38” |
| dc:title | Title (literal) | “Protein Alkylation leading to Liver Fibrosis” |
| dcterms:alternative | Alternative title (literal) | “Protein Alkylation to Liver Fibrosis” |
| dc:creator | Author (literal) | “““Brigitte Landesmann… |
| dcterms:abstract | Abstract (literal) | “““Hepatotoxicity in general is of special interest… |
| nci:C54571 | Stressor (IRI)* | aop.stressor:9,aop.stressor: 13,aop.stressor:60,… |
| aopo:has_key_event | Key Event (IRI)* | aop.events:55,aop.events:1492,aop.events:1493, … |
| aopo:has_molecular_initiating_event | Key Event (IRI)* | aop.events:244 |
| aopo:has_adverse_outcome | Key Event (IRI)* | aop.events:344 |
| aopo:has_key_event_relationship | Key Event Relationship (IRI)* | aop.relationships:269,aop.relationships:1718, … |
| dc:description | Description (literal) | “““Two prototypical chemicals acting via protein alkylation are … |
| pato:0000047 | Sex applicability (literal) | “Unspecific” |
| aopo:LifeStageContext | Life stage applicability (literal) | “Not Otherwise Specified” |
| aopo:AopContext | Applicability (literal) | “““The described AOP is valid for both sexes and any life stage … |
| edam:operation_3799 | Quantitative considerations (literal) | “““More advanced in vitro models systems are needed … |
| aopo:has_evidence | Weight of evidence (literal) | “““Support for Essentiality of KEs … |
| nci:C25725 | Potential applications (literal) | “““This systematic and coherent display of currently available … |
| nci:C25217 | Overall assessment (literal) | “““Assessment of the Weight-of-Evidence supporting the AOP … |
| nci:C48192 | Key Event essentiality (literal) | “““The essentiality of each of the KEs for this AOP … |
| dc:accessRights | AOP status (literal) | “Open for citation & comment” |
| foaf:page | Webpage (URL) | <https://identifiers.org/aop/38> |
| dcterms:created | Date of creation (literal) | “2016-11-29T18:41:16” |
| dcterms:modified | Date of latest modification (literal) | “2019-04-30T12:53:51” |
| dc:source | Source (literal) | “AOPWiki” |
Asterisks indicate the object IRIs that connect to other subjects in the RDF.