Fig. 1.

There is variable mRNA expression of bitter (T2R) taste receptor genes in HNSCC. (A) Quantitative PCR (qPCR) expression analysis of T2R transcripts from biopsy specimens of HNSCC (‘SCC’) compared with contralateral normal tissue (‘control’) from the same patient (mean ± SEM; 10 patients). Expression of each TAS2R mRNA was normalized to ubiquitin C (UBC) housekeeping gene. No significant differences in individual TAS2R gene expression between cancer and control samples by two‐way ANOVA with Bonferroni posttest. (B) Heatmap representation of the same T2R transcript data, grouped by individual patients.