Table 3.
Ten Clinical and Metabolomic Variables with the Highest Absolute Loading Factors
| Variable name | Biological meaning | Block | Loading |
|---|---|---|---|
| Waist | Waist circumference | Clinical_PRS | −0.420 |
| BMI | BMI (kg/m2) | Clinical_PRS | −0.389 |
| HIP | Hip circumference | Clinical_PRS | −0.306 |
| FB LEUK | Leucocytes | Clinical_PRS | −0.304 |
| B MONOS | Monocytes | Clinical_PRS | −0.271 |
| B NEUT | Neutrophils | Clinical_PRS | −0.250 |
| B HB | Hemoglobin | Clinical_PRS | −0.250 |
| SEX | Sex (M/F) | Clinical_PRS | 0.241 |
| B LYMF | Lymphocytes | Clinical_PRS | −0.229 |
| B HKR | Haematocrit | Clinical_PRS | −0.229 |
| Gp | Glycoprotein acetylation | Metabolomics | −0.197 |
| Ile | Isoleucine | Metabolomics | −0.194 |
| Leu | Leucine | Metabolomics | −0.188 |
| LHDLFC | Free cholesterol in large HDL | Metabolomics | 0.184 |
| XLHDLP | co of very large HDL particles | Metabolomics | 0.179 |
| TGPG | ro triglycerides/phosphoglycerides | Metabolomics | −0.169 |
| PUFAFA | ro polyunsaturated f.a/total f.a | Metabolomics | 0.168 |
| LHDLPL | Phospholipids/total lipids ro (LHDL) | Metabolomics | 0.161 |
| IDLFC | Free cholesterol/total lipids ro (IDL) | Metabolomics | 0.160 |
| LHDLPL | Phospholipids in LHDL | Metabolomics | −0.157 |
co, concentration; f.a, fatty acid; LHDL, large high-density lipoprotein; ro, ratio.