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. 2022 Mar 17;36(7-9):550–566. doi: 10.1089/ars.2021.0047

FIG. 4.

FIG. 4.

Cumulative sodium and volume excretion is delayed in male wild-type mice compared with Noxa1−/− male and female wild-type mice during the initial phase of AIH. Time to excrete 75% of the sodium (A) and water (B) following the acute isotonic saline load in male wild-type and Noxa1−/− mice during the control period and Ang II infusion days 1–2 and 13–14. Data are mean ± SEM % over control. Time to excrete 75% of the sodium (C) and water (D) following the acute salt load in female wild-type and Noxa1−/− mice during the control period and Ang II administration for 1–2 days. Data are mean ± SEM % over control. AIH, Ang II-induced hypertension.