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. 2022 Mar 21;10:850191. doi: 10.3389/fpubh.2022.850191

Table 5.

Diagnostic performance of laboratory-related indicators in pregnant women with GDM.

Indicators Youden index Cutoff AUC AUC 95% CI Sensitivity Specificity PPV (%) NPV (%)
Age 0.1277 30.5 0.586 0.5332–0.6394 49.65 63.12 30.19 79.61
Pre-pregnancy BMI 0.5436 21.84 0.817 0.7734–0.8604 70.42 83.94 58.48 89.83
FPG 0.3178 4.825 0.702 0.6510–0.7524 65.49 66.29 38.42 85.67
PT 0.2151 11.55 0.589 0.5300–0.6473 45.77 75.74 37.73 81.30
INR 0.2165 0.965 0.591 0.5322–0.6496 36.62 85.03 44.00 80.68
APTT 0.2482 27.75 0.670 0.6195–0.7187 69.72 55.1 33.28 85.00
FIB 0.16 4.136 0.600 0.5464–0.6533 43.66 72.34 33.64 79.99
TT 0.2171 15.65 0.643 0.5914–0.6954 64.79 56.92 32.57 83.43
TC 0.1857 5.21 0.602 0.5469–0.6574 53.19 65.38 33.04 81.30
TG 0.2828 1.735 0.679 0.6280–0.7299 63.12 65.16 36.78 84.62
LDL-C 0.1895 2.965 0.635 0.5823–0.6877 46.1 72.85 35.29 80.80
sdLDL-C 0.3481 393.8 0.710 0.6605–0.7594 58.57 76.24 44.19 85.14
APOB 0.1963 0.975 0.603 0.5472–0.6592 46.1 73.53 35.87 80.94
APOE 0.2249 36.5 0.624 0.5747–0.6736 86.52 35.97 30.26 89.26
Combined test 0.6756 0.238 0.892 0.8581–0.9268 80.71 86.85 66.43 93.34