Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 21;13:839424. doi: 10.3389/fphar.2022.839424

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Hollingsworth, Wang, White, Simpson and Jablonski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Funduscopy and fluorescein angiography reveal retinal phenotypes consistent with RP. WT and BXD32 retinas were observed under white light for funduscopy (A) and using 488 nm for fluorescein angiography (B) light post-fluorescein injection. By funduscopy, BXD32 mice as early as p84 begin showing RPE through the neural retina (asterisks, *) indicating a major loss of photoreceptors in these regions. Fluorescein angiography reveals vessel attenuation in the superficial vascular plexus (arrowheads, >) beginning around p63 with some regions exhibiting vaso-obliteration, mostly in the intermediate and deep vascular plexi (asterisk, *).