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. 2022 Mar 21;9:843410. doi: 10.3389/fsurg.2022.843410

Table 3.

Main results of subgroup meta-analysis.

Index n RR SMD 95% CI P I2 % P for heterogeneity Model
HVA (RCT only) 8 NA −0.08 −0.50 ~ 0.34 0.53 76 P < 0.01 REM
HVA (non-RCT only) 13 NA −0.2 −0.43 ~ 0.03 0.03 63 P < 0.01 REM
HVA (2G MIS) 9 NA −0.08 −0.31 ~ 0.15 0.51 46 0.06 FEM
HVA (3G MIS) 9 NA −0.4 −0.68 ~ 0.13 P < 0.01 69 P < 0.01 REM
IMA (RCT only) 9 NA −0.25 −0.58 ~ 0.08 0.14 63 P < 0.01 REM
IMA (non-RCT only) 13 NA −0.09 −0.33 ~ 0.14 0.42 72 P < 0.01 REM
IMA (2G MIS) 9 NA −0.28 −0.57 ~ 0.01 0.04 64 P < 0.01 REM
IMA (3G MIS) 9 NA 0.01 −0.30 ~ 0.31 0.96 75 P < 0.01 REM
DMAA (RCT only) 5 NA −0.19 −0.46 ~ 0.06 0.14 0 0.72 FEM
DMAA (non-RCT only) 5 NA −0.44 −0.87 ~ 0.02 0.04 71 P < 0.01 REM
DMAA (2G MIS) 5 NA −0.14 −0.38 ~ 0.11 0.27 0 0.71 FEM
DMAA (3G MIS) 3 NA −0.79 −1.08 ~−0.49 P < 0.01 35 0.21 FEM
AOFAS score (RCT only) 7 NA 0.45 0.03 ~ 0.87 0.04 73 P < 0.01 REM
AOFAS score (non-RCT only) 10 NA 0.14 −0.25 ~ 0.53 0.48 89 P < 0.01 REM
AOFAS score (2G MIS) 7 NA 0.37 −0.17 ~ 0.90 0.18 88 P < 0.01 REM
AOFAS score (3G MIS) 8 NA 0.17 −0.22 ~ 0.56 0.39 83 P < 0.01 REM
Complication rate (RCT only) 8 1.03 NA 0.68 ~ 1.57 0.89 28 0.21 FEM
Complication rate (non-RCT only) 12 1.12 NA 0.70 ~ 1.82 0.62 52 0.01 REM
Complication rate (2G MIS) 9 1.05 NA 0.55 ~ 2.02 0.88 65 P < 0.01 REM
Complication rate (3G MIS) 9 1.07 NA 0.76 ~ 1.51 0.71 0 0.47 FEM

N, number of included studies; RR, risk ratio; SMD, standardized mean difference; CI, confidence interval; RCT, randomized controlled trial; HVA, hallux valgus angle; 2G, second generation; 3G, third generation; MIS, minimally invasive surgery; NA, not applicable; FEM, fixed effect model; REM, random effect model; IMA, first intermetatarsal angle; DMAA, distal metatarsal articular angle; AOFAS, the American Orthopedic Foot and Ankle Society.