TABLE 3.
Percent identity between the amino acid sequences of class B carbapenem-hydrolyzing β-lactamasesa
| β-Lactamase | % Identity
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| VIM-2 | VIM-1 | B-II | IMP-1 | CcrA | BlaB | IND-1 | CphA-1 | L-1 | GOB-1 | |
| VIM-1 | 90 | |||||||||
| B-II | 32 | 35 | ||||||||
| IMP-1 | 31 | 28 | 31 | |||||||
| CcrA | 27 | 27 | 28 | 34 | ||||||
| BlaB | 24 | 24 | 32 | 27 | 25 | |||||
| IND-1 | 24 | 24 | 33 | 28 | 27 | 40 | ||||
| CphA-1 | 21 | 23 | 26 | 19 | 20 | 25 | 23 | |||
| L-1 | 11 | 13 | 12 | 9 | 11 | 9 | 11 | 12 | ||
| GOB-1 | 4 | 4 | 10 | 12 | 10 | 11 | 12 | 13 | 18 | |
a
The origins of the β-lactamases are as follows: VIM-2, P. aeruginosa COL-1; VIM-1, P. aeruginosa VR 143-97 (10); B-II, B. cereus (8); IMP-1, various gram-negative rods, including P. aeruginosa (15); BlaB, C. meningosepticum CCUG4310 (21); IND-1, Chryseobacterium indologenes 001 (2); CcrA, Bacteroides fragilis TAL 3636 (19); CphA-1, Aeromonas hydrophila AE036 (12); L-1, Stenotrophomonas maltophilia IID1275 (25); GOB-1, C. meningosepticum (GenBank accession no. AF90141).