. Author manuscript; available in PMC: 2022 Apr 4.

Published in final edited form as: Allergy. 2021 Mar 15;76(8):2510–2523. doi: 10.1111/all.14762

TABLE 1.

Available subjects with whole-genome sequencing data within the Atopic Dermatitis Research Network included in the gene-based tests for eczema herpeticum

Trait	Atopic Dermatitis without Eczema Herpeticum (ADEH−) Cases	Atopic Dermatitis with Recurrent Eczema Herpeticum (ADEH+) Cases	Non-atopic (NA) Controls	p-value ADEH+ vs. ADEH− ADEH− vs. NA ADEH+ vs. NA
N	491	49	237
Males (N; %)	221 (45.0%)	24 (49.0%)	72 (30.4%)	0.5950
				< 0.001
				0.0134
Age^a (Years); mean (SD)	28.0 (18.4)	21.4 (15.6)	37.4 (13.8)	0.0162
Age^a (Years); mean (SD)				< 0.001
				< 0.001
Total IgE(kU/L) mean (range)	2188.4 (2.0–82020.0)	3775.8 (14.4–2416.0)	23.8 (2.2–306.0)	< 0.001
Total IgE(kU/L) mean (range)				< 0.001
				< 0.001
Eosinophils mean (range)	337.1 (4.0–2502.0)	454.8 (22.0–1409.0)	114.2 (0–421.0)	0.0052
Eosinophils mean (range)				< 0.001
				< 0.001
Phadiatop (kUA/L) mean (range)	103.9 (0.1–5632.0)	215.8 (0.2–4181.0)	0.3 (0.1–0.4)	0.0041
				< 0.001
				< 0.001
EASI mean (range)	14.4 (0.3–66.8)	15.4 (0–55.0)	N/A	0.8803
EASI mean (range)				N/A
				N/A
Rajka-Langeland score mean (SD)	6.9 (1.5)	6.9 (1.7)	N/A	0.8812
				N/A
				N/A

Abbreviation: SD, standard deviation.

Age at recruitment, not age at diagnosis.