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Structural changes during molecular dynamic simulation: (A) Superimposed root mean square deviation (RMSD) and root mean square fluctuation (RMSF) spectrum of wild-type (black) and mutant proteins [S194* (recovered) shown in green and S194L (mortality) shown in red] during 200 ns of molecular dynamics simulation period. (B) The obtained simulated structures of mutated N protein with wild type.
