Table 3.

Suggested classification of polyuria and dehydration in the ICI-induced CDI syndrome.

Grade	1 (mild)	2 (moderate)	3 (severe)	4 (life-threatening)	5
Polyuria	<3 ml/kg/h	3÷7 ml/kg/h	>7 ml/kg/h	Any grade polyuria + moderate-severe dehydration ± moderate-severe hypernatremia	Death
Dehydration	Loss of <3% body weight in 2 hours	Loss of 3 ÷ 5% body weight in 2 hours	Loss of 6 ÷ 9% body weight in 2 hours	Loss of ≥10% body weight in 2 hours or shock	Death