FIGURE 3.

Numbers of hippocampal cells immunopositive for total tau, Ser202/Thr205-phosphorylated tau, and Aβ. Tissues from hippocampus of wild-type (WT) and Tyrobp^–/– mice aged 6 months were immunostained for total tau (tau-5), Ser202/Thr205-phosphorylated tau (AT8), and Aβ (6E10). (A) Representative micrographs. (B–D) Quantification of total tau, Ser202/Thr205-phosphorylated tau, and Aβ. Data are mean ± SEM from three independent experiments (three mice per group). Differences were assessed for significance using Student’s t test.