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Reduced m6A RNA methyltransferases in the hippocampus of Tyrobp–/– mice. (A) Relative levels of Mettl3, Mettl14, and Wtap mRNAs encoding methyltransferases and of Fto and Alkbh5 mRNAs encoding demethylases. (B,C) Western blotting and quantification of METTL3, METTL14 and WTAP in the hippocampus. Data are mean ± SEM (six or nine mice per group). Differences were assessed for significance using Student’s t test.
