Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 21;16:739201. doi: 10.3389/fnins.2022.739201

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Lv, Xu, Li, Zheng, Li, Li, Yang and Hao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Volcano plots, heatmaps, Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enriched in genes differentially expressed between wild-type (WT) and Tyrobp^–/– mice. (A) Volcano plots and (B) heatmap showing genes and transcripts differentially expressed between WT and Tyrobp^–/– mice. (C) Quantitative real-time PCR detection of six genes chosen from the methylated RNA immunoprecipitation sequencing data. (D,E) Major GO terms and KEGG pathways were analyzed for genes upregulated by Tyrobp knockout. (F,G) Major GO terms and KEGG pathways were analyzed for genes downregulated by Tyrobp knockout. Up- or downregulation was defined, respectively, as fold change ≥ 2 or fold change ≤ –2 combined with P < 0.05. Nine mice were used in each group.