FIGURE 1.

Characterization of vasorelaxation in four pigmented RBEs in porcine coronary artery rings. Arterial rings with the endothelium were contracted with U46619 before the addition of increasing concentrations of red, brown, green, and black RBEs (1 μg/ml to 100 μg/ml) to construct the concentration-relaxation curves. (A) Representative original tracing and (B) corresponding cumulative concentration-relaxation curve. The relaxation response is expressed as the percentage relaxation of the U46619-induced contraction. Results are presented as means ± SEM (n = 6–8). ***p < 0.001 vs control. **p < 0.01 vs control.