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. 2022 Mar 21;9:817294. doi: 10.3389/fmolb.2022.817294

FIGURE 2.

FIGURE 2

Construction of descriptors of miRNAs and small molecules. The table in blue presents a vector of 277 RNA features (i.e., descriptors) for each miRNA sequence. For example, RNA Feature_1 represents the length of a miRNA sequence, and RNA Festure_277 represents the frequency of ‘UUUU’ in the miRNA sequence. The table in orange presents a vector of 166 fingerprints transformed from the SMILES string of each small molecule. “0” and “1” represent the absence and presence of a substructure in each small molecule, respectively. The table in yellow presents the ‘0’ and “1” labels for negative (not binding) and positive (binding) regulation pairs of miRNAs and small molecules, respectively.