TABLE 1.

Prediction performance of models for up-regulation pairs using the 5-fold cross validation on the training dataset.

Model	ROC	Sens	Spec	ROCSD	SensSD	SpecSD
GLM	0.853	0.770	0.767	0.0247	0.0263	0.0447
KNN	0.878	0.783	0.804	0.0151	0.0338	0.0403
SVM	0.887	0.812	0.814	0.0232	0.035	0.0506
ANN	0.852	0.798	0.727	0.0205	0.0439	0.0486
RF	0.905	0.825	0.823	0.00718	0.0131	0.0178