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. 2022 Mar 21;13:842150. doi: 10.3389/fimmu.2022.842150

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Copyright © 2022 Gibellini, De Biasi, Meschiari, Gozzi, Paolini, Borella, Mattioli, Lo Tartaro, Fidanza, Neroni, Busani, Girardis, Guaraldi, Mussini, Cozzi-Lepri and Cossarizza

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Plasma level of several cytokines and chemokines stratified controls and cases. Upper panel: principal-component analysis (PCA) analysis of cytokines, chemokines and other soluble molecules quantified across the cohort. Lower panel: a plot displays the variables as vectors, indicating the direction of each variable to the overall distribution. The strength of each variable is represented by colors: orange colour represents a strong contribution, light blue colour represents a milder contribution.