Determination of vincristine in plasma samples and relative recovery of spiked vincristine in these samplesa.
Plasma samples | Added (mg L−1) | Found, mean ± SDb (n = 3) (mg L−1) | Relative recovery (%) |
---|---|---|---|
Taken from a 10 year-old girl | 0 | 5.2 ± 0.4 | — |
5 | 10.6 ± 1.2 | 107.7 | |
Taken from a 12 year-old boy | 0 | 9.3 ± 0.8 | — |
10 | 20.1 ± 1.6 | 108.6 | |
Taken from a 13 year-old girl | 0 | 2.5 ± 0.3 | — |
15 | 17.3 ± 1.4 | 92.0 | |
Taken from a 16 year-old boy | 0 | 13.2 ± 1.1 | — |
20 | 34.1 ± 2.4 | 106.8 |
These data are based on the diluted volumes of plasma samples and dilution effect was considered for calculation of them.
Standard deviation.