Table 3.

Cells viability of SH-SY5Y cell line after incubation with compounds 16–21 and tacrine for 24 h (% of control).

Compounds	12.5 µM	50 µM	100 µM
16	88.06 ± 7.8	80.04 ± 7.7	83.47 ± 8.6
17	94.42 ± 5.1	67.73 ± 14.7**	63.18 ± 12.2**
18	79.50 ± 7.4	71.25 ± 20.5	58.99 ± 20.3*
19	85.46 ± 12.6	82.59 ± 3.2*	81.12 ± 5.0
20	78.91 ± 8.6*	79.69 ± 1.1*	68.63 ± 14.5***
21	52.27 ± 5.0***	42.72 ± 6.4***	30.67 ± 1.5***
Tacrine	98.74 ± 4.5	97.25 ± 2.1	68.90 ± 2.9***

Means ± SD from triplicates from at least three different experiments. *p < 0.05; **p < 0.01; ***p < 0.001, as compared to the control.