Table 5.

Cytotoxicity of compounds 16–21 and tacrine on HepG2 cells.

Compounds	IC50 [µM]
16	113.9
17	72.28
18	53.83
19	>600
20	134.5
21	–
Tacrine	189.9

The IC₅₀, was calculated from the following equation: log (inhibitor) versus responses curve using the GraphPad Prism 5 program.