Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 1;29(1):1025–1037. doi: 10.1080/10717544.2022.2057616

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 5. — In vivo therapeutic efficacy evaluation. (A) Schematic depicting the experimental procedure of arthritis induction and intravenous treatment with NPs in rats. Photographs (B) and micro-CT images (C) representative hind legs after treatment in different treatment groups. Quantification of articular index score (D), paw thickness (E) after different treatments over time. Quantitative analysis of bone volume over total volume ratio (BV/TV) (F), trabecular number (Tb.N) (G), trabecular thickness (Tb.Th) (H), and ratio of bone surface area to bone volume (BS/BV) (I) of CIA rats in different treated groups. Results were presented as mean ± SD (n = 3). *p < .05, ***p < .001, ****p < .0001 vs saline. ^#p < .05, ^##p < 0.01, and ^####p < 0.0001, pDNA-NPs or DSP-NPs vs pDNA/DSP-NPs (two-tailed unpaired Student’s t-test).