. Author manuscript; available in PMC: 2022 Apr 4.
Published in final edited form as: Nature. 2017 Nov 20;552(7685):378–381. doi: 10.1038/nature25020
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
Reprints and permissions information is available at www.nature.com/reprints