Table 3.

Performance of predictive models for late grade ≥2 genitourinary toxicity after conventionally-fractionated radiotherapy or stereotactic body radiotherapy.

	Sensitivity	Specificity	PPV	NPV	F1 Score	AUC
Prediction of Toxicity after CF-RT
Random Forest	0.77	0.80	0.42	0.95	0.54	0.78
Elastic Net	0.59	0.96	0.71	0.93	0.65	0.76
Boosted Trees	0.65	0.97	0.79	0.94	0.71	0.81
Prediction of Toxicity after SBRT
Random Forest	0.86	0.76	0.39	0.97	0.53	0.81
Elastic Net	0.79	0.92	0.65	0.96	0.71	0.87
Boosted Trees	0.71	0.90	0.56	0.95	0.63	0.81

AUC, area under the curve; -RT, conventionally fractionated RT; NPV, negative predictive value; PPV, positive predictive value; SBRT, stereotactic body radiotherapy.