Appendix 3—table 2. Results from ${\chi }^2$-test of independence (with Yates’ continuity correction) between A (an epistatic interaction screened by our search is identified in our search) and B (an epistatic interaction screened by our search is identified by Costanzo et al., 2016) at three levels of stringency for B, as described in the text.

Overlap is the number of gene interactions identified by both studies.

Stringency level	P(A|B’)	P(A|B)	Overlap	${\chi }^2$	$p_{{\chi }^2,\text{df}=1}$
Lenient	2.32%	2.25%	494	0.37	0.54
Intermediate	2.29%	2.44%	187	0.62	0.43
Stringent	2.29%	2.86%	96	4.46	0.03