KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-Ki67	Thermo	Cat# RM9106, RRID:AB_2341197
Anti-IL-17	Santa Cruz	Cat# SC-7927, RRID:AB_2124997
Anti-LPS core	Hyacult Biotech	Cat# WN1 222–5, RRID:AB_2750644
Anti-MPO	DAKO	Cat# A0398
Anti-CCL3	Pierce	Cat# OA1653721, RRID: AB_1956667
Bacterial and virus strains
B fragilis NCTC9343	ATCC	Cat# 25285
B. thetaiotamicron	ATCC	Cat# 29148
Biological samples
B fragilis clinical isolates	This study	N/A
Proximal colon biopsies	This study	N/A
Critical commercial assays
Human IL-8 ELISA	Becton Dickinson	Cat # 555244
Human IL-10 ELISA	Becton Dickinson	Cat # 555157
Human IL-12p40 ELISA	Becton Dickinson	Cat # 555171
Human IL-1b ELISA	Invitrogen	Cat # KHC001
Nextera DNA Flex Library Prep kits	Illumina	Cat# 20018705
bacterial DNA extraction kit	Qiagen	Cat#158567
dual luciferase assay reporter system	Promega	Cat # E2920
Deposited data
16S Phylum level LDA analysis of biopsies	This study	https://doi.org/10.5281/zenodo.5090347
16S DNA fastQ files	This study	https://doi.org/10.5281/zenodo.5090347
Whole genome sequencing of B fragilis isolates	This study	https://doi.org/10.5281/zenodo.5090347
Whole genome sequencing fastQ files	This study	https://doi.org/10.5281/zenodo.5090347
Experimental models: Cell lines
Human: HEK293 cells	ATCC	CRL-1573
Human: THP-1 cells	ATCC	TIB-202
Experimental models: Organisms/strains
Human colon biopsies	This study	N/A
B. fragilis clinical isolates	This study	N/A
Oligonucleotides
Primer bft Forward, GCGAACTCGGTTTAPTGCAGT Reverse, GTTGTAPGACATCCCACTGGC26	DeJea et al., 2018	N/A
Primer glycosyltransferase Forward, ACCTAAGAGCGCACGGAA and Reverse, AGGTCGTCCGAATAPGCCA.	This paper	N/A
Software and algorithms
Comparative genomics	Galperin et al 2015. https://github.com/StoreyLab/qvalue	N/A
ASNP identification	Seemann, 2020	N/A
CLC genomics suite	Qiagen	N/A
LDA	https://huttenhower.sph.harvard.edu/galaxy/]	N/A
Anvio	Eren et al., 2015. http://merenlab.org/software/anvio/	N/A