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. Author manuscript; available in PMC: 2023 Feb 3.
Published in final edited form as: Breast Cancer Res Treat. 2022 Feb 3;192(1):153–161. doi: 10.1007/s10549-021-06475-2

Table 2.

Relationship between treatment, physical, and cardiac functioning:* NSABP B-36

Treatment Change from baseline to 12 months
Physical Functioning LVEF
Overall −1.74 (−4.03, 0.55) −2.61 (−3.39,−1.83)
AC −0.46 (−3.64, 2.71) −2.61 (−3.70, −1.53)
FEC-100 −3.18 (−6.49, 0.14) −2.65 (−3.79, −1.52)
Difference FEC-100 vs. AC −2.72 (−7.33, 1.89) −0.04 (−1.61, 1.53)
P value 0.25 0.96
*

Changes are model-based and adjusted for age and corresponding baseline measure; evaluated at average age of 51.8 and average baseline PF-10 score of 79.4, or average baseline LVEF score of 64.8.