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. 2022 Mar 21;12:861151. doi: 10.3389/fonc.2022.861151

Table 1.

Correlations between clinicopathological and vascular index (VI) values of breast cancers.

Number VI (%)M (25%~75%) Z P value
Size(cm) -0.819 0.413
≤2 94 7.7 (4.0~13.4)
>2 131 7.0 (4.4~11.3)
ER status -2.361 0.018
Positive 158 6.7 (4.0~10.8)
Negative 67 8.8 (5.1~18.2)
PR status -1.835 0.066
Positive 134 6.6 (3.9~10.8)
Negative 91 8.2 (4.4~14.2)
HER-2 status -0.516 0.606
Negative 181 7.4 (4.3~12.1)
Positive 44 6.7 (4.1~11.6)
Ki-67 index (%) -1.650 0.099
<14 45 5.9 (2.7~11.3)
≥14 180 7.6 (4.4-12.4)
Ki-67 index (%) 5.563 0.062
<14 45 5.9 (2.7~11.3)
14~20 20 6.8 (2.6~9.3)
≥20 160 7.7 (4.5~12.7)
Ki-67 index (%) -2.322 0.020
<20 65 6.2 (2.7~10.8)
≥20 160 7.7 (4.5~12.7)
Histology
Invasive ductal carcinoma 210 7.5 (4.3~12.1) 2.931 0.231
Invasive lobular carcinoma
Others
4
11
5.4 (1.5~12.0)
4.8 (1.4~9.5)
Nuclear grade 6.792 0.034
1 32 5.3 (1.8~9.6)
2 101 7.3 (4.3~12.4)
3 92 8.2 (4.5~13.7)
Axillary lymph node metastasis -0.009 0.992
Absent 138 7.6 (3.8~13.3)
Present 87 7.0 (4.7~10.6)
Stage 2.646 0.449
I 66 8.5 (4.1~13.8)
II 137 7.0 (4.3~11.4)
III 21 6.5 (4.6~11.8)
IV 1 11.7

VI (%)M (25%~75%), Vascular index (%) Median (25%~75%); ER, estrogen receptor; HER-2, human epidermal growth factor receptor-2.

The difference is statistically significant in bold.