. 2022 Mar 28;2022:1445604. doi: 10.1155/2022/1445604

Table 2.

The percent inhibition of alpha-amylase and alpha-glucosidase of the synthesized compounds.

Compound	Conc. (µg/ml)	% inhibitions (α-glucosidase)	IC₅₀ (μg/ml)	% inhibitions (α-amylase)	IC₅₀ (μg/ml)
BW1	500	89.08 ± 1.04^ns	10.49	81.60 ± 0.00^∗∗∗	13.90
	250	83.45 ± 0.90^ns		75.32 ± 0.40^∗∗∗
	125	76.58 ± 0.63^ns		71.78 ± 0.44^∗∗∗
	62.50	70.40 ± 0.20^ns		65.08 ± 0.66^∗∗∗
	31.25	65.80 ± 0.90^ns		57.40 ± 0.40^∗∗∗

BW2	500	87.36 ± 0.49^∗	10.81	78.69 ± 0.14^∗∗∗	15.34
	250	81.34 ± 0.55^∗		73.14 ± 0.49^∗∗∗
	125	74.39 ± 0.49^∗∗∗		67.44 ± 0.15^∗∗∗
	62.50	68.47 ± 0.52^∗∗∗		63.72 ± 0.11^∗∗∗
	31.25	62.44 ± 0.55^∗∗		55.85 ± 0.17^∗∗∗

BW3	500	77.85 ± 2.24^∗∗∗	12.15	75.35 ± 0.89^∗∗∗	18.20
	250	72.08 ± 0.47^∗∗∗		71.36 ± 1.15^∗∗∗
	125	67.90 ± 0.96^∗∗∗		67.62 ± 0.03^∗∗∗
	62.50	63.28 ± 0.57^∗∗∗		62.16 ± 0.12^∗∗∗
	31.25	57.47 ± 0.56^∗∗∗		54.67 ± 0.35^∗∗∗

Acarbose	500	92.23 ± 0.22	8.20	87.75 ± 0.42	10.35
	250	86.45 ± 0.90		82.47 ± 0.71
	125	80.90 ± 0.60		76.20 ± 0.49
	62.50	73.00 ± 0.30		69.42 ± 1.55
	31.25	67.90 ± 0.45		63.62 ± 0.58

All values are taken as mean ± SEM (n = 3), and two-way ANOVA followed by Bonferroni test were followed. Values significantly different as compared to standard drug; ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, and ns: not significant.