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. 2022 Mar 28;2022:9419918. doi: 10.1155/2022/9419918

Figure 2.

Figure 2

Folecitin reduced Aβ via inhibiting BACE-1 expression. (a) Immunoblots of BACE1 and Aβ in the brain homogenates of the adult mice for the experimental groups including (c) LPS, LPS + F, and F alone. Histogram of (b) BACE1 and (c) Aβ. β-Actin was used as a house-keeping loading control (reference control). The bands were analysed using the Image J software, and the density histograms (expressed in AU) compared to the control were organized using GraphPad Prism. Values are presented as the mean ± SEM for the indicated proteins (n = 6 mice per group). C: control, LPS: lipopolysaccharide, F: folecitin, AU: arbitrary units, #P < 0.05 and ###P < 0.001 as compared to the C group, and ∗P < 0.05 and ∗∗∗P < 0.001 as compared to the LPS group.