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. 2022 Mar 28;2022:9419918. doi: 10.1155/2022/9419918

Figure 4.

Figure 4

Folecitin stimulated the phosphorylated-Akt (p-Akt) to activate Nrf-2/HO-1. (a) Immunoblots of p-Akt, HO-1, and Nrf-2 proteins for the experimental groups including (c) LPS, LPS + F, and F alone. Histogram of (b) p-Akt, (c) Nrf-2, and (d) HO-1 proteins. β-Actin was used as a loading control (reference control). The bands were analysed using the Image J software, and the density histograms (expressed in AU) compared to the control were organized using GraphPad Prism. Values are presented as the mean ± SEM for the indicated proteins (n = 6 mice per group). C: control, LPS: lipopolysaccharide, F: folecitin, AU: arbitrary units, ##P < 0.01 and ###P < 0.001 as compared to the C group, and ∗∗P < 0.01 and ∗∗∗P < 0.001 as compared to the LPS group.