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. 2022 Mar 21;12:856974. doi: 10.3389/fonc.2022.856974

Figure 1.

Figure 1

Normal breast architecture and breast cancer subtypes. (A) Representative image of breast architecture showing lobular and ductal system. (B) Magnified view of milk duct showing detailed lobular and ductal structure as an inset image. (C) Cross-sectional view of normal mammary duct showing basement membrane, basal myoepithelial cell layer, and luminal or epithelial cell layer from outside to inside. (D) Representative images of ductal carcinoma in situ (DCIS) and (E) invasive ductal carcinoma (IDC). (F) Representative images of lobular carcinoma in situ (LCIS) and (G) invasive lobular carcinoma (ILC). (H) Histological subtypes (preinvasive and invasive) and (I) molecular subtypes (triple-negative, HER2+, luminal A, and luminal B) of breast cancer.