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. 2022 Jan 14;36(4):901–912. doi: 10.1038/s41375-021-01502-z

Table 1.

Association of EC50 values of BH3-mimetics with protein levels.

BCL-2 BCL-XL MCL-1
Venetoclax rs –0.480 0.171 0.530
p 0.018* 0.424 0.008*
S63845 rs –0.120 0.117 0.357
p 0.577 0.585 0.087
A-1331852 rs 0.174 –0.263 0.034
p 0.418 0.214 0.873

Association of EC50 values of BH3-mimetics with protein levels of target molecules. Patient-derived xenograft BCP-ALL (N = 24). Spearman correlation; r, correlation coefficient; p, significance; * p ≤ 0.05.