Table 1. Data source and characteristics of included participants and phenotypes.
| Phenotypes | Meana | Mean (SD)b | Consortium | Number of variants | Samplesize |
| Exposures | |||||
| Group (a) | |||||
| Apo A1, g/L | 1.70 | 0.89 (0.32) | Kettunen et al | 11,760,646 | 20,687 |
| Apo B, g/L | 0.98 | 0.81 (0.52) | Kettunen et al | 11,813,266 | 20,690 |
| TC, mmol/L | 5.37 | 0.45 (0.39) | Kettunen et al | 11,855,845 | 21,491 |
| TG, mmol/L | 1.18 | 1.05 (0.14) | Kettunen et al | 11,871,391 | 21,545 |
| LDL-C, mmol/L | 2.11 | 19.00 (0.27) | Kettunen et al | 11,871,461 | 21,559 |
| HDL-C, mmol/L | 1.69 | 2.62 (0.32) | Kettunen et al | 11,865,530 | 21,555 |
| Group (b) | |||||
| XXL.VLDL.TG, mmol/L | 0.01 | 13.80 (0.53) | Kettunen et al | 11,843,388 | 21,540 |
| XL.VLDL.TG, mmol/L | 0.03 | 9.00 (0.56) | Kettunen et al | 11,814,232 | 21,548 |
| L.VLDL.TG, mmol/L | 0.12 | 0.98 (0.98) | Kettunen et al | 11,753,671 | 21,239 |
| M.VLDL.TG, mmol/L | 0.24 | 0.52 (1.53) | Kettunen et al | 11,766,530 | 21,241 |
| S.VLDL.TG, mmol/L | 0.23 | 5.16 (0.22) | Kettunen et al | 11,859,725 | 21,558 |
| XS.VLDL.TG, mmol/L | 0.11 | 0.38 (0.51) | Kettunen et al | 11,820,655 | 19,273 |
| IDL.TG, mmol/L | 0.11 | NA | Kettunen et al | 11,820,642 | 19,273 |
| XL.HDL.TG, mmol/L | 0.01 | 34.00 (0.14) | Kettunen et al | 11,871,386 | 21,536 |
| S.HDL.TG, mmol/L | 0.04 | 10.10 (0.61) | Kettunen et al | 11,871,440 | 21,558 |
| Outcome | |||||
| Coronary heart disease | — | — | CARDIoGRAM plusC4D | 9,455,779 | 184,305 |
| Myocardial infarction | — | — | CARDIoGRAM plusC4D | 9,289,492 | 171,875 |
| Ischemic stroke | — | — | ISGC | 2,421,920 | 29,633 |
| Cardioembolic stroke | — | — | ISGC | 2,421,920 | 21,185 |
| Large vessel disease | — | — | ISGC | 2,421,920 | 21,143 |
| Small vessel disease | — | — | ISGC | 2,421,920 | 20,675 |
Apo, apolipoprotein; HDL-C, high-density lipoprotein cholesterol; IDL, intermediate density lipoprotein; LDL-C, low-density lipoprotein cholesterol; SD, standard deviation; TC, total cholesterol; TG, triglycerides; VLDL, very low density lipoprotein; XXL.VLDL.TG, triglycerides in largest VLDL; XL.VLDL.TG, triglycerides in very large VLDL; L.VLDL.TG, triglycerides in large VLDL; M.VLDL.TG, triglycerides in medium VLDL; S.VLDL.TG, triglycerides in small VLDL; XS.VLDL.TG, triglycerides in very small VLDL; IDL.TG, triglycerides in IDL; XL.HDL.TG, triglycerides in very large HDL; S.HDL.TG, triglycerides in small HDL; NA, not available.
aSummary statistics of untransformed distributions from the largest cohort, Northern Finland Birth Cohort 1966 (NFBC 1966).
bSummary statistics of untransformed distributions from the cohort, Erasmus Rucphen Family Study (ERF).
Note: The unit of exposures (phenotypes column) showed in group (a) and group (b) were the unit used in the NFBC 1966 cohort corresponding to the second column. The values of all Mean/SD were recorded from the initial GWAS research reported by Kettunen et al (the supplement material of reference 14).