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. 2022 Apr 4;8:157. doi: 10.1038/s41420-022-00963-0

Table 2.

Multivariate analysis for overall survival of NB patients in the NRC cohort.

Variables HR 95.0% CI p value
MYCN amplification 4.967 1.118–22.066 0.035
High EIF4EBP1 mRNA expression 3.031 1.543–5.954 0.001
MYCN amplification*high EIF4EBP1 mRNA expression 0.656 0.135–3.181 0.601
Stage 4 15.050 4.239–53.432 0.018
High EIF4EBP1 mRNA expression 5.144 1.330–19.895 0
Stage 4*high EIF4EBP1 mRNA expression 0.36 0.081–1.598 0.179
Age at diagnosis 0.27 0.036–2.056 0
High EIF4EBP1 mRNA expression 0.364 0.048–2.772 0.002
Age at diagnosis*high EIF4EBP1 mRNA expression 55.427 3.258–942.88 0.005