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. 2022 Apr 4;12:5636. doi: 10.1038/s41598-022-09085-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cytokine induction from human whole blood by P. intermedia biofilm and planktonic cells. Human whole blood collected from a healthy volunteer was stimulated by secretome preparations from the biofilms and planktonic cultures of P. intermedia for 24 h. The cytokines produced were detected by using Proteome Profiler™ membrane array. Means (SD) of signal densities of spots were determined using Gene Tools analysis software in Syngene Imaging System.