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. 2021 Dec 17;126(7):1018–1026. doi: 10.1038/s41416-021-01649-7

Table 2.

Therapeutic efficacies.

mFOLFIRINOX (N = 27) GOFL (N = 28) Total (N = 55)
Best response to ICT
 Partial response 6 (22.2%) 4 (14.3%)
 Stable disease 20 (74.1%) 18 (64.3%)
 Progressive disease 1 (3.7%) 6 (21.4%)
 Disease control rate 26 (96.3%) 22 (78.6%)
Response after CCRT
 Partial response 6 4
 Stable disease 7 11
 Progressive disease 8 2
Per-protocol R0/R1 resection 1 (3.7%) 5 (17.8%) 6 (10.9%)
Median (95% CI) PFS, months 6.6 (5.9–12.5) 7.6 (3.9–12.3) 6.7 (6.2–8.3)
9-month PFS rate 30.5% 35.9% 33.3%
Median (95% CI) OS, months 19.6 (13.4–22.9) 17.9 (13.4–23.9) 18.7 (15.8–21.9)
 12-month OS rate (%) 88.9 (69.4–96.3) 82.1 (62.3–92.2) 85.5 (73.0–92.4)
 24-month OS rate (%) 29.6 (14.1–47.0) 31.8 (15.7–49.1) 30.8 (19.2–43.1)