Table 3.

Univariate and multivariate regression analyses for baseline eGFR in patients with type 2 diabetes with microalbuminuria and macroalbuminuria

	Univariate				Multivariate
	Correlation coefficient (r)	Regression coefficient	Standard error	p value	Correlation coefficient (r)	Regression coefficient	Standard error	p value
Microalbuminuria (n = 124)
Sex (male)	0.000	0.009	1.879	0.996
BMI	0.007	0.394	0.394	0.386
Duration of diabetes	− 0.148	− 0.352	0.219	0.111
Mean blood pressure	0.213	0.389	0.159	0.017	0.088	0.158	0.145	0.279
HbA1c	0.404	6.714	1.374	< 0.001	0.39	6.350	1.282	< 0.001
Urinary albumin excretion	− 0.054	− 0.013	0.022	0.551
Total cholesterol	0.144	0.088	0.055	0.113
HDL-cholesterol	0.121	0.187	0.139	0.193
Triglyceride	− 0.007	− 0.001	0.016	0.929
Plaque in carotid artery	− 0.355	− 1.046	0.254	< 0.001	− 0.319	− 0.942	0.238	0.010
								(R2 = 0.270 p < 0.001)
Macroalbuminuria (n = 81)
Sex (male)	0.026	0.609	2.537	0.811
BMI	0.168	0.712	0.470	0.134
Duration of diabetes	− 0.287	− 0.662	0.265	0.015	− 0.258	− 0.605	0.264	0.025
Mean blood pressure	0.111	0.155	0.156	0.323
HbA1c	0.205	3.833	2.053	0.065	0.205	3.34	1.796	0.067
Urinary protein excretion	− 0.358	− 6.226	1.862	0.001	− 0.214	− 3.909	2.081	0.065
Total cholesterol	− 0.140	− 0.011	0.009	0.256
HDL-cholesterol	− 0.244	− 0.049	0.036	0.185
Triglyceride	− 0.100	− 0.003	0.002	0.175
Plaque in carotid artery	− 0.355	− 1.046	0.254	< 0.001	− 0.241	− 0.768	0.37	0.042
								(R2 = 0.227, p < 001)

Independent variables comprise the baseline value of eGFR (before the start of diabetes dialysis prevention). Mean blood pressure = diastolic pressure + systolic pressure-diastolic pressure/3. Plaque in the carotid artery is the sum of the plaque thickness in the carotid artery

BMI body mass index, eGFR estimated glomerular filtration rate, HDL high-density lipoprotein, UAC urinary albumin-to-creatinine excretion rate, UPC urinary protein-to-creatinine excretion rate