Table 5. Comparisons between TPHPT and NCPHPT.
| Variables | TPHPT (n = 158) | NCPHPT (n = 27) | P value | |
|---|---|---|---|---|
| Age, yr | 59.3 ± 14.0 | 54.6 ± 16.3 | 0.114 | |
| Age < 50 yr | 33 (20.9%) | 10 (37.0%) | 0.066 | |
| Sex, n | 0.290 | |||
| Male | 38 (24.1%) | 4 (14.8%) | ||
| Female | 120 (75.9%) | 23 (85.2%) | ||
| BMD (n = 132, 19) | 0.012a | |||
| Normal | 15 (11.4%) | 6 (31.6%) | ||
| Osteopenia | 51 (38.6%) | 2 (10.5%) | ||
| Osteoporosis | 66 (50.0%) | 11 (57.9%) | ||
| T-score (lumbar) (n = 132, 19) | −2.4 ± 1.2 | −2.2 ± 1.4 | 0.521 | |
| Nephrolithiasis, n | 28 (17.7%) | 2 (7.4%) | 0.179 | |
| Bone fracture, n | 13 (8.2%) | 2 (7.4%) | 0.885 | |
| Preop PTH, pg/mL | 212.7 ± 219.3 | 99.1 ± 24.5 | 0.008a | |
| Preop sCa, mg/dL | 11.4 ± 1.1 | 10.0 ± 0.7 | < 0.001a | |
| Preop iCa, mg/dL | 5.8 ± 0.4 | 4.9 ± 0.3 | < 0.001a | |
| Preop P, mg/dL | 2.6 ± 0.5 | 3.2 ± 0.5 | < 0.001a | |
| Preop 25-OH-Vit D, ng/mL | 19.3 ± 9.4 | 20.1 ± 8.6 | 0.682 | |
| 24hr urine calcium, mg/24hr | 324.3 ± 178.2 | 315.7 ± 169.3 | 0.848 | |
| eGFR, mL/min/1.73m2 | 80.4 ± 11.9 | 85.5 ± 7.8 | 0.006a | |
All continuous variables expressed as mean ± standard deviation.
TPHPT = typical primary hyperparathyroidism, NCPHPT = normocalcemic primary hyperparathyroidism with normal ionized calcium, BMD = bone mineral density, PTH = parathyroid hormone, sCa = serum calcium, iCa = ionized calcium, P = phosphorus, 25-OH-Vit D = 25-hydroxy-vitamin D, eGFR = estimated glomerular filtration rate.
aStatistical significance.