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. 2022 Feb 11;15(2):288–298. doi: 10.14202/vetworld.2022.288-298

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Copyright: © Jati, et al.

Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Figure-1 — Model of competitive inhibition of piperine (PIP) on the components of the Mitogen-activated protein kinases/NF-B axis. (a) Visualization of the 3D PIP ligand interaction with the JNK-1 active site. (b) Visualization of the 3D PIP ligand interaction with the active site of inhibitor of nuclear factor-kappa B kinase beta subunit.