Table 3.
Results from linear mixed effects models including cortical thickness. The lmer function automatically performed t-tests using Satterthwaite approximations to estimate degrees of freedom. Values describe relationships between diffusion white matter measures (FD, FC, FDC, AWF and TORT) and grey matter cortical thickness (CTh) measures in MS and MOGAD patients. (FD: fibre density, FC: fibre cross-section, FDC: fibre density and cross-section, AWF: axonal water fraction, TORT: tortuosity).
| Patient Group | WM metrics | CTh | CI (95%) | padj-value |
|---|---|---|---|---|
| MS | FD | 0.011 | −0.006,0.028 | 0.22 |
| MOGAD | FD | 0.003 | −0.011,0.016 | 0.71 |
| MS | FC | 0.048 | 0.012,0.084 | 0.015 |
| MOGAD | FC | 0.030 | −0.014,0.075 | 0.20 |
| MS | FDC | 0.021 | −0.007,0.049 | 0.15 |
| MOGAD | FDC | 0.011 | −0.014,0.036 | 0.39 |
| MS | AWF | 0.004 | −0.004,0.012 | 0.35 |
| MOGAD | AWF | 0.005 | −0.003,0.012 | 0.24 |
| MS | TORT | 0.082 | 0.003,0.160 | 0.051 |
| MOGAD | TORT | 0.026 | −0.034,0.089 | 0.43 |