Table 1.
CD8 (a) and CD4 (b) T cell epitopes of SARS CoV2/human/USA/CA CZB 1055/2020 isolate showing number of aliphatic amino acids and immunogenicity (Ig) score (Hopp and Woods 1981)
| Name of proteins | CD8 T- cell epitopes (a) | Aliphatic amino acids | Ig analysis of epitopes | |
|---|---|---|---|---|
| Hydropathy index | Immunogenicity score | |||
| Surface glycoprotein | PDPSKPSKR | 2 | 6.97 | 9.2 |
| DPSKPSKRS | 2 | 6.88 | 9.01 | |
| DYNYKLPDD | 2 | 6.53 | 8.23 | |
| WNSNNLDSK | 2 | 6.34 | 8.12 | |
| QTQTNSPRR | 0 | 7.09 | 8.08 | |
| Membrane glycoprotein | TDHSSSSDN | 0 | 6.46 | 8.72 |
| NTDHSSSSD | 0 | 6.46 | 8.72 | |
| DHSSSSDNI | 1 | 5.88 | 7.59 | |
| GNYKLNTDH | 3 | 6.3 | 7.56 | |
| NYKLNTDHS | 2 | 6.34 | 7.48 | |
| Envelope protein | YSRVKNLNS | 3 | 5.64 | 6.37 |
| KPSFYVYSR | 2 | 5.3 | 5.72 | |
| VYSRVKNLN | 4 | 5.09 | 5.24 | |
| YSFVSEETG | 2 | 4.94 | 4.99 | |
| FYVYSRVKN | 3 | 4.96 | 4.86 | |
| Name of proteins | CD4 T- cell epitopes (b) | Aliphatic amino acids | Ig analysis of epitopes | |
|---|---|---|---|---|
| Hydropathy index | Immunogenicity score | |||
| Surface glycoprotein | NSNNLDSKVGGNYNY | 5 | 5.96 | 7.81 |
| WNSNNLDSKVGGNYN | 5 | 5.93 | 7.71 | |
| ASYQTQTNSPRRARS | 2 | 6.31 | 6.94 | |
| AWNSNNLDSKVGGNY | 6 | 5.58 | 6.92 | |
| HRSYLTPGDSSSGWT | 3 | 5.61 | 6.84 | |
| Membrane glycoprotein | GNYKLNTDHSSSSDN | 3 | 6.26 | 8.14 |
| NYKLNTDHSSSSDNI | 3 | 5.93 | 7.29 | |
| IGNYKLNTDHSSSSD | 4 | 5.73 | 7.05 | |
| RIGNYKLNTDHSSSS | 4 | 5.79 | 6.95 | |
| RYRIGNYKLNTDHSS | 4 | 6.07 | 6.92 | |
| Envelope protein | KPSFYVYSRVKNLNS | 5 | 5.23 | 5.70 |
| VKPSFYVYSRVKNLN | 6 | 4.89 | 5.04 | |
| SLVKPSFYVYSRVKN | 6 | 4.71 | 4.80 | |
| LVKPSFYVYSRVKNL | 7 | 4.41 | 4.23 | |
| YSFVSEETGTLIVNS | 5 | 4.27 | 4.14 | |