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. 2022 Mar 22;9:848499. doi: 10.3389/fcvm.2022.848499

Table 5.

Comparison of patient information and target vessel characteristics according to percent QFR increase of the target vessel.

Low %QFR increase ≤23%
(n = 62)
High %QFR increase >23%
(n = 178)
t/Z/χ2 P
Male (%) 47 (75.8) 134 (75.3) 0.007 0.934
Age (years) 61.53 ± 10.54 63.29 ± 9.83 1.188 0.236
Hypertension (%) 20 (32.3) 71 (39.9) 1.137 0.286
Duration of hypertension (years) 12.00 (7.00, 15.75) 10.00 (3.00, 18.00) 0.062 0.950
Diabetes mellitus (%) 19 (30.6) 46 (25.8) 0.537 0.464
Duration of diabetes mellitus (years) 5.00 (2.00, 8.00) 5.00 (3.00, 9.00) 0.737 0.461
Current smoking (%) 30 (48.4) 77 (43.3) 0.490 0.484
Current smoking cigarettes per day 20.00 (10.00, 20.00) 15.00 (5.00, 20.00) 1.124 0.261
Duration of smoking (years) 15.00 (8.75, 23.50) 19.00 (13.75, 25.50) 1.788 0.074
Current drinking (%) 17 (27.4) 39 (21.9) 0.780 0.377
Family history of CAD (%) 8 (12.9) 21 (11.8) 0.053 0.818
History of myocardial infarction 6 (9.7) 13 (7.3) 0.356 0.551
Previous PCI (%) 16 (25.8) 51 (28.7) 0.185 0.667
Clinical presentation 2.994 0.084
Unstable angina pectoris 51 (82.3) 161 (90.4)
NSTEMI 11 (17.7) 17 (9.6)
Average heart rate (beats/min) 71.29 ± 7.29 70.01 ± 6.68 1.268 0.206
SDNN 113.50 (81.50, 136.00) 110.00 (90.75, 134.25) 0.120 0.904
SDANN 99.50 (73.25, 120.50) 90.50 (73.00, 109.25) 1.667 0.096
rMSSD 41.00 (25.75, 61.50) 41.50 (28.75, 66.00) 0.681 0.496
Pnn50 7.00 (2.75, 18.25) 7.00 (3.00, 15.00) 0.332 0.740
Total power (ms2) 1,933.05 (1,290.48, 2,820.45) 2,039.40 (1,361.50, 3,251.30) 0.801 0.423
LF (ms2) 119.65 (53.06, 212.74) 144.25 (93.51, 246.23) 2.658 0.008
HF (ms2) 109.60 (60.85,227.50) 131.20 (67.78, 252.13) 0.943 0.346
LF/HF 0.92 (0.62, 1.50) 1.28 (0.76, 1.82) 2.618 0.009
DC 24h ms 2.84 ± 1.50 2.79 ± 1.35 0.214 0.830
Target vessel characteristics
Number of diseased vessels 2.15 ± 0.88 2.14 ± 0.82 0.038 0.970
Number of implanted stents 1.77 ± 0.95 1.83 ± 1.06 0.339 0.735
Target vascular location 3.776 0.151
LAD 35 (56.5) 79 (44.4)
LCX 13 (21.0) 36 (20.2)
RCA 14 (22.6) 63 (35.4)
Minimal lumen diameter 0.87 ± 0.38 0.84 ± 0.38 0.549 0.583
Maximum area stenosis 81.43 ± 9.07 85.11 ± 9.83 2.552 0.011
Lesion length of target vessels 16.30 (11.30, 25.93) 16.40 (10.20, 25.90) 0.625 0.532
Pre-PCI QFR 0.72 ± 0.08 0.65 ± 0.08 5.989 <0.001
% QFR increase 0.16 (0.12, 0.20) 0.40 (0.31, 0.55) 11.473 <0.001
Post-PCI QFR 0.86 (0.80, 0.91) 0.94 (0.91, 0.97) 7.146 <0.001